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An Opsin 5-dopamine pathway mediates light-dependent vascular development in the eye

During mouse postnatal eye development, the embryonic hyaloid vascular network regresses from the vitreous as an adaption for high acuity vision. This process occurs with precisely controlled timing. Here we show that an Opsin 5 (OPN5, Neuropsin)-dependent retinal light response regulates vascular d...

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Detalles Bibliográficos
Autores principales: Nguyen, Minh-Thanh T., Vemaraju, Shruti, Nayak, Gowri, Odaka, Yoshinobu, Buhr, Ethan D., Alonzo, Nuria, Tran, Uyen, Batie, Mathew, Upton, Brian A., Darvas, Martin, Kozmik, Zbynek, Rao, Sujata, Hegde, Rashmi S., Iuvone, P. Michael, Van Gelder, Russell N., Lang, Richard A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573021/
https://www.ncbi.nlm.nih.gov/pubmed/30936473
http://dx.doi.org/10.1038/s41556-019-0301-x