Mechanistic basis of L-lactate transport in the SLC16 solute carrier family

In human and other mammalian cells, transport of L-lactate across plasma membranes is mainly catalyzed by monocarboxylate transporters (MCTs) of the SLC16 solute carrier family. MCTs play an important role in cancer metabolism and are promising targets for tumor treatment. Here, we report the crysta...

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Detalles Bibliográficos
Autores principales: Bosshart, Patrick D., Kalbermatter, David, Bonetti, Sara, Fotiadis, Dimitrios
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573034/
https://www.ncbi.nlm.nih.gov/pubmed/31201333
http://dx.doi.org/10.1038/s41467-019-10566-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573034/
https://www.ncbi.nlm.nih.gov/pubmed/31201333
http://dx.doi.org/10.1038/s41467-019-10566-6

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