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Mediator complex interaction partners organize the transcriptional network that defines neural stem cells

The Mediator complex regulates transcription by connecting enhancers to promoters. High Mediator binding density defines super enhancers, which regulate cell-identity genes and oncogenes. Protein interactions of Mediator may explain its role in these processes but have not been identified comprehens...

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Detalles Bibliográficos
Autores principales: Quevedo, Marti, Meert, Lize, Dekker, Mike R., Dekkers, Dick H. W., Brandsma, Johannes H., van den Berg, Debbie L. C., Ozgür, Zeliha, van IJcken, Wilfred F. J., Demmers, Jeroen, Fornerod, Maarten, Poot, Raymond A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573065/
https://www.ncbi.nlm.nih.gov/pubmed/31209209
http://dx.doi.org/10.1038/s41467-019-10502-8