eIF4G2 balances its own mRNA translation via a PCBP2-based feedback loop

Poly(rC)-binding protein 2 (PCBP2, hnRNP E2) is one of the most abundant RNA-binding proteins in mammalian cells. In humans, it exists in seven isoforms, which are assumed to play similar roles in cells. The protein is shown to bind 3′-untranslated regions (3′-UTRs) of many mRNAs and regulate their...

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Detalles Bibliográficos
Autores principales: Smirnova, Victoria V., Shestakova, Ekaterina D., Bikmetov, Dmitry V., Chugunova, Anastasia A., Osterman, Ilya A., Serebryakova, Marina V., Sergeeva, Olga V., Zatsepin, Timofey S., Shatsky, Ivan N., Terenin, Ilya M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573783/
https://www.ncbi.nlm.nih.gov/pubmed/31010886
http://dx.doi.org/10.1261/rna.065623.118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573783/
https://www.ncbi.nlm.nih.gov/pubmed/31010886
http://dx.doi.org/10.1261/rna.065623.118

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