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Antagonism between the RNA-binding protein Musashi1 and miR-137 and its potential impact on neurogenesis and glioblastoma development

RNA-binding proteins (RBPs) and miRNAs are critical gene expression regulators that interact with one another in cooperative and antagonistic fashions. We identified Musashi1 (Msi1) and miR-137 as regulators of a molecular switch between self-renewal and differentiation. Msi1 and miR-137 have opposi...

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Detalles Bibliográficos
Autores principales: Velasco, Mitzli X., Kosti, Adam, Guardia, Gabriela D.A., Santos, Marcia C., Tegge, Allison, Qiao, Mei, Correa, Bruna R.S., Hernández, Greco, Kokovay, Erzsebet, Galante, Pedro A.F., Penalva, Luiz O.F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6573790/
https://www.ncbi.nlm.nih.gov/pubmed/31004009
http://dx.doi.org/10.1261/rna.069211.118