Prolonged day length exposure improves circadian deficits and survival in a transgenic mouse model of Huntington's disease

The circadian disruption seen in patients of Huntington's disease (HD) is recapitulated in the R6/2 mouse model. As the disease progresses, the activity of R6/2 mice increases dramatically during the rest (light) period and decreases during the active (dark) period, eventually leading to a comp...

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Detalles Bibliográficos
Autores principales: Ouk, Koliane, Aungier, Juliet, Morton, A. Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6575567/
https://www.ncbi.nlm.nih.gov/pubmed/31236493
http://dx.doi.org/10.1016/j.nbscr.2016.11.004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6575567/
https://www.ncbi.nlm.nih.gov/pubmed/31236493
http://dx.doi.org/10.1016/j.nbscr.2016.11.004

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