Comparison of quantitative trait loci methods: Total expression and allelic imbalance method in brain RNA-seq

BACKGROUND: Of the 108 Schizophrenia (SZ) risk-loci discovered through genome-wide association studies (GWAS), 96 are not altering the sequence of any protein. Evidence linking non-coding risk-SNPs and genes may be established using expression quantitative trait loci (eQTL). However, other approache...

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Detalles Bibliográficos
Autores principales: Gådin, Jesper R., Buil, Alfonso, Colantuoni, Carlo, Jaffe, Andrew E., Nielsen, Jacob, Shin, Joo-Heon, Hyde, Thomas M., Kleinman, Joel E., Plath, Niels, Eriksson, Per, Brunak, Søren, Didriksen, Michael, Weinberger, Daniel R., Folkersen, Lasse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576752/
https://www.ncbi.nlm.nih.gov/pubmed/31206532
http://dx.doi.org/10.1371/journal.pone.0217765

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576752/
https://www.ncbi.nlm.nih.gov/pubmed/31206532
http://dx.doi.org/10.1371/journal.pone.0217765

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