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Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause
OBJECTIVE: An early onset of menarche and, later, menopause are well-established risk factors for the development of breast cancer and endometrial cancer. Although the largest GWASs have identified 389 independent signals for age at menarche (AAM) and 44 regions for age at menopause (ANM), GWAS can...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576755/ https://www.ncbi.nlm.nih.gov/pubmed/31206546 http://dx.doi.org/10.1371/journal.pone.0213953 |