Integrating genome-wide association and eQTLs studies identifies the genes associated with age at menarche and age at natural menopause

OBJECTIVE: An early onset of menarche and, later, menopause are well-established risk factors for the development of breast cancer and endometrial cancer. Although the largest GWASs have identified 389 independent signals for age at menarche (AAM) and 44 regions for age at menopause (ANM), GWAS can...

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Detalles Bibliográficos
Autores principales: Wang, Gang, Lv, Jian, Qiu, Xiaoxin, An, Yujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576755/
https://www.ncbi.nlm.nih.gov/pubmed/31206546
http://dx.doi.org/10.1371/journal.pone.0213953

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