Cargando…

RNA structural analysis of the MYC mRNA reveals conserved motifs that affect gene expression

The MYC gene encodes a human transcription factor and proto-oncogene that is dysregulated in over half of all known cancers. To better understand potential post-transcriptional regulatory features affecting MYC expression, we analyzed secondary structures in the MYC mRNA using a program that is opti...

Descripción completa

Detalles Bibliográficos
Autores principales: O’Leary, Collin A., Andrews, Ryan J., Tompkins, Van S., Chen, Jonathan L., Childs-Disney, Jessica L., Disney, Matthew D., Moss, Walter N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576772/
https://www.ncbi.nlm.nih.gov/pubmed/31206539
http://dx.doi.org/10.1371/journal.pone.0213758