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Increased compensatory kidney workload results in cellular damage in a short time porcine model of mixed acidemia – Is acidemia a ‘first hit’ in acute kidney injury?

Acute kidney injury (AKI) corrupts the outcome of about 50% of all critically ill patients. We investigated the possible contribution of the pathology acidemia on the development of AKI. Pigs were exposed to acidemia, acidemia plus hypoxemia or a normal acid-base balance in an experimental setup, wh...

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Detalles Bibliográficos
Autores principales: Russ, Martin, Ott, Sascha, Bedarf, Janis R., Kirschfink, Michael, Hiebl, Bernhard, Unger, Juliane K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576776/
https://www.ncbi.nlm.nih.gov/pubmed/31206554
http://dx.doi.org/10.1371/journal.pone.0218308