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Conformational coupling by trans-phosphorylation in calcium calmodulin dependent kinase II

The calcium calmodulin-dependent protein kinase II (CaMKII) is a dodecameric holoenzyme important for encoding memory. Its activation, triggered by binding of calcium-calmodulin, persists autonomously after calmodulin dissociation. One (receiver) kinase captures and subsequently phosphorylates the r...

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Detalles Bibliográficos
Autores principales: Pandini, Alessandro, Schulman, Howard, Khan, Shahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576796/
https://www.ncbi.nlm.nih.gov/pubmed/31150387
http://dx.doi.org/10.1371/journal.pcbi.1006796