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Conformational coupling by trans-phosphorylation in calcium calmodulin dependent kinase II
The calcium calmodulin-dependent protein kinase II (CaMKII) is a dodecameric holoenzyme important for encoding memory. Its activation, triggered by binding of calcium-calmodulin, persists autonomously after calmodulin dissociation. One (receiver) kinase captures and subsequently phosphorylates the r...
Autores principales: | Pandini, Alessandro, Schulman, Howard, Khan, Shahid |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6576796/ https://www.ncbi.nlm.nih.gov/pubmed/31150387 http://dx.doi.org/10.1371/journal.pcbi.1006796 |
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