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SB203580, a p38MAPK inhibitor, attenuates olfactory dysfunction by inhibiting OSN apoptosis in AR mice (activation and involvement of the p38 mitogen‐activated protein kinase in olfactory sensory neuronal apoptosis of OVA‐induced allergic rhinitis)

OBJECTIVE: This study aimed to investigate the effect of the p38 mitogen‐activated protein kinase (p38MAPK) signaling pathway on olfactory mucosa function and apoptosis of olfactory sensory neurons (OSNs) in an allergic rhinitis (AR) mouse model. METHOD: Fifty‐five BALB/c mice were used to establish...

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Detalles Bibliográficos
Autores principales: Gao, Xian, Li, Na, Zhang, Jisheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6577615/
https://www.ncbi.nlm.nih.gov/pubmed/31041850
http://dx.doi.org/10.1002/brb3.1295