The priming factor CAPS1 regulates dense-core vesicle acidification by interacting with rabconnectin3β/WDR7 in neuroendocrine cells

Vacuolar-type H(+)-ATPases (V-ATPases) contribute to pH regulation and play key roles in secretory and endocytic pathways. Dense-core vesicles (DCVs) in neuroendocrine cells are maintained at an acidic pH, which is part of the electrochemical driving force for neurotransmitter loading and is require...

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Detalles Bibliográficos
Autores principales: Crummy, Ellen, Mani, Muralidharan, Thellman, John C., Martin, Thomas F. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2019
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579465/
https://www.ncbi.nlm.nih.gov/pubmed/31004036
http://dx.doi.org/10.1074/jbc.RA119.007504

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579465/
https://www.ncbi.nlm.nih.gov/pubmed/31004036
http://dx.doi.org/10.1074/jbc.RA119.007504

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