SCAF4 and SCAF8, mRNA Anti-Terminator Proteins

Accurate regulation of mRNA termination is required for correct gene expression. Here, we describe a role for SCAF4 and SCAF8 as anti-terminators, suppressing the use of early, alternative polyadenylation (polyA) sites. The SCAF4/8 proteins bind the hyper-phosphorylated RNAPII C-terminal repeat doma...

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Detalles Bibliográficos
Autores principales: Gregersen, Lea H., Mitter, Richard, Ugalde, Alejandro P., Nojima, Takayuki, Proudfoot, Nicholas J., Agami, Reuven, Stewart, Aengus, Svejstrup, Jesper Q.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579486/
https://www.ncbi.nlm.nih.gov/pubmed/31104839
http://dx.doi.org/10.1016/j.cell.2019.04.038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579486/
https://www.ncbi.nlm.nih.gov/pubmed/31104839
http://dx.doi.org/10.1016/j.cell.2019.04.038

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