Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA

Cohesin mediates higher order chromosome structure. Its biological activities require topological entrapment of DNA within a lumen(s) formed by cohesin subunits. The reversible dissociation of cohesin’s Smc3p and Mcd1p subunits is postulated to form a regulated gate that allows DNA entry and exit in...

Descripción completa

Detalles Bibliográficos
Autores principales: Guacci, Vincent, Chatterjee, Fiona, Robison, Brett, Koshland, Douglas E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Chromosomes and Gene Expression
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579514/
https://www.ncbi.nlm.nih.gov/pubmed/31162048
http://dx.doi.org/10.7554/eLife.46347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579514/
https://www.ncbi.nlm.nih.gov/pubmed/31162048
http://dx.doi.org/10.7554/eLife.46347

Ejemplares similares