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Communication between distinct subunit interfaces of the cohesin complex promotes its topological entrapment of DNA

Cohesin mediates higher order chromosome structure. Its biological activities require topological entrapment of DNA within a lumen(s) formed by cohesin subunits. The reversible dissociation of cohesin’s Smc3p and Mcd1p subunits is postulated to form a regulated gate that allows DNA entry and exit in...

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Detalles Bibliográficos
Autores principales:	Guacci, Vincent, Chatterjee, Fiona, Robison, Brett, Koshland, Douglas E
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2019
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579514/ https://www.ncbi.nlm.nih.gov/pubmed/31162048 http://dx.doi.org/10.7554/eLife.46347

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