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Mechanism of completion of peptidyltransferase centre assembly in eukaryotes

During their final maturation in the cytoplasm, pre-60S ribosomal particles are converted to translation-competent large ribosomal subunits. Here, we present the mechanism of peptidyltransferase centre (PTC) completion that explains how integration of the last ribosomal proteins is coupled to releas...

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Detalles Bibliográficos
Autores principales: Kargas, Vasileios, Castro-Hartmann, Pablo, Escudero-Urquijo, Norberto, Dent, Kyle, Hilcenko, Christine, Sailer, Carolin, Zisser, Gertrude, Marques-Carvalho, Maria J, Pellegrino, Simone, Wawiórka, Leszek, Freund, Stefan MV, Wagstaff, Jane L, Andreeva, Antonina, Faille, Alexandre, Chen, Edwin, Stengel, Florian, Bergler, Helmut, Warren, Alan John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579518/
https://www.ncbi.nlm.nih.gov/pubmed/31115337
http://dx.doi.org/10.7554/eLife.44904