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Mechanism of completion of peptidyltransferase centre assembly in eukaryotes
During their final maturation in the cytoplasm, pre-60S ribosomal particles are converted to translation-competent large ribosomal subunits. Here, we present the mechanism of peptidyltransferase centre (PTC) completion that explains how integration of the last ribosomal proteins is coupled to releas...
Autores principales: | Kargas, Vasileios, Castro-Hartmann, Pablo, Escudero-Urquijo, Norberto, Dent, Kyle, Hilcenko, Christine, Sailer, Carolin, Zisser, Gertrude, Marques-Carvalho, Maria J, Pellegrino, Simone, Wawiórka, Leszek, Freund, Stefan MV, Wagstaff, Jane L, Andreeva, Antonina, Faille, Alexandre, Chen, Edwin, Stengel, Florian, Bergler, Helmut, Warren, Alan John |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579518/ https://www.ncbi.nlm.nih.gov/pubmed/31115337 http://dx.doi.org/10.7554/eLife.44904 |
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