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The dynamic conformational landscape of the protein methyltransferase SETD8

Elucidating the conformational heterogeneity of proteins is essential for understanding protein function and developing exogenous ligands. With the rapid development of experimental and computational methods, it is of great interest to integrate these approaches to illuminate the conformational land...

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Detalles Bibliográficos
Autores principales: Chen, Shi, Wiewiora, Rafal P, Meng, Fanwang, Babault, Nicolas, Ma, Anqi, Yu, Wenyu, Qian, Kun, Hu, Hao, Zou, Hua, Wang, Junyi, Fan, Shijie, Blum, Gil, Pittella-Silva, Fabio, Beauchamp, Kyle A, Tempel, Wolfram, Jiang, Hualiang, Chen, Kaixian, Skene, Robert J, Zheng, Yujun George, Brown, Peter J, Jin, Jian, Luo, Cheng, Chodera, John D, Luo, Minkui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579520/
https://www.ncbi.nlm.nih.gov/pubmed/31081496
http://dx.doi.org/10.7554/eLife.45403