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A single cell transcriptional portrait of embryoid body differentiation and comparison to progenitors of the developing embryo

Directed differentiation of pluripotent stem cells provides an accessible system to model development. However, the distinct cell types that emerge, their dynamics, and their relationship to progenitors in the early embryo has been difficult to decipher because of the cellular heterogeneity inherent...

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Detalles Bibliográficos
Autores principales: Spangler, Abby, Su, Emily Y., Craft, April M., Cahan, Patrick
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579609/
https://www.ncbi.nlm.nih.gov/pubmed/30118958
http://dx.doi.org/10.1016/j.scr.2018.07.022