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Simultaneous protection of tissue physicochemical properties using polyfunctional crosslinkers
Understanding complex biological systems requires the system-wide characterization of both molecular and cellular features. Existing methods for spatial mapping of biomolecules in intact tissues suffer from information loss caused by degradation and tissue damage. We report a tissue transformation s...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579717/ https://www.ncbi.nlm.nih.gov/pubmed/30556815 http://dx.doi.org/10.1038/nbt.4281 |