Simultaneous protection of tissue physicochemical properties using polyfunctional crosslinkers

Understanding complex biological systems requires the system-wide characterization of both molecular and cellular features. Existing methods for spatial mapping of biomolecules in intact tissues suffer from information loss caused by degradation and tissue damage. We report a tissue transformation s...

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Detalles Bibliográficos
Autores principales: Park, Young-Gyun, Sohn, Chang Ho, Chen, Ritchie, McCue, Margaret, Yun, Dae Hee, Drummond, Gabrielle T., Ku, Taeyun, Evans, Nicholas B., Oak, Hayeon Caitlyn, Trieu, Wendy, Choi, Heejin, Jin, Xin, Lilascharoen, Varoth, Wang, Ji, Truttmann, Matthias C., Qi, Helena W., Ploegh, Hidde L., Golub, Todd R., Chen, Shih-Chi, Frosch, Matthew P., Kulik, Heather J., Lim, Byung Kook, Chung, Kwanghun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579717/
https://www.ncbi.nlm.nih.gov/pubmed/30556815
http://dx.doi.org/10.1038/nbt.4281

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