Gasdermin D protects against noninfectious liver injury by regulating apoptosis and necroptosis

Gasdermin D (GsdmD) was recently identified as the executioner of pyroptotic inflammatory cell death, and is a substrate for caspases-1 and 11. GsdmD is detrimental in lethal endotoxemia but protective in bacterial sepsis. However, little is known about its role during noninfectious/sterile injuries...

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Detalles Bibliográficos
Autores principales: Yang, Chenxuan, Sun, Ping, Deng, Meihong, Loughran, Patricia, Li, Wenbo, Yi, Zhongjie, Li, Shilai, Zhang, Xianghong, Fan, Jie, Billiar, Timothy R., Scott, Melanie J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579760/
https://www.ncbi.nlm.nih.gov/pubmed/31209224
http://dx.doi.org/10.1038/s41419-019-1719-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579760/
https://www.ncbi.nlm.nih.gov/pubmed/31209224
http://dx.doi.org/10.1038/s41419-019-1719-6

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