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The role of properdin in complement-mediated renal diseases: a new player in complement-inhibiting therapy?
Properdin is known as the only positive regulator of the complement system. Properdin promotes the activity of this defense system by stabilizing its key enzymatic complexes: the complement alternative pathway (AP) convertases. Besides, some studies have indicated a role for properdin as an initiato...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579773/ https://www.ncbi.nlm.nih.gov/pubmed/30141176 http://dx.doi.org/10.1007/s00467-018-4042-z |