A Phase 2, Randomized, Double-Blind, Placebo-Controlled Trial of CX-8998, a Selective Modulator of the T-Type Calcium Channel in Inadequately Treated Moderate to Severe Essential Tremor: T-CALM Study Design and Methodology for Efficacy Endpoint and Digital Biomarker Selection

Background: Essential tremor (ET) is a common, progressive neurological syndrome with bilateral upper-limb dysfunction of at least 3-year duration, with or without tremor in other body locations. This disorder has a negative impact on daily function and quality of life. A single oral therapy has bee...

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Detalles Bibliográficos
Autores principales: Papapetropoulos, Spyros, Lee, Margaret S., Boyer, Stacey, Newbold, Evan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neurology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579833/
https://www.ncbi.nlm.nih.gov/pubmed/31244760
http://dx.doi.org/10.3389/fneur.2019.00597

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579833/
https://www.ncbi.nlm.nih.gov/pubmed/31244760
http://dx.doi.org/10.3389/fneur.2019.00597

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