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The Glycosylation Site of Myelin Oligodendrocyte Glycoprotein Affects Autoantibody Recognition in a Large Proportion of Patients

Autoantibodies to myelin oligodendrocytes glycoprotein (MOG) are found in a fraction of patients with inflammatory demyelination and are detected with MOG-transfected cells. While the prototype anti-MOG mAb 8-18C5 and polyclonal anti-MOG responses from different mouse strains largely recognize the F...

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Detalles Bibliográficos
Autores principales: Marti Fernandez, Iris, Macrini, Caterina, Krumbholz, Markus, Hensbergen, Paul J., Hipgrave Ederveen, Agnes L., Winklmeier, Stephan, Vural, Atay, Kurne, Asli, Jenne, Dieter, Kamp, Frits, Gerdes, Lisa Ann, Hohlfeld, Reinhard, Wuhrer, Manfred, Kümpfel, Tania, Meinl, Edgar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579858/
https://www.ncbi.nlm.nih.gov/pubmed/31244828
http://dx.doi.org/10.3389/fimmu.2019.01189