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Cholesterol-rich lipid-mediated nanoparticles boost of transfection efficiency, utilized for gene editing by CRISPR-Cas9

Purpose: Gene therapy has become a promising remedy to treat disease by modifying the person’s genes. The therapeutic potential of related tools such as CRISPR-Cas9 depends on the efficiency of delivery to the targeted cells. Numerous transfection reagents have been designed and lots of efforts have...

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Detalles Bibliográficos
Autores principales: Hosseini, Elaheh Sadat, Nikkhah, Maryam, Hosseinkhani, Saman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579871/
https://www.ncbi.nlm.nih.gov/pubmed/31354265
http://dx.doi.org/10.2147/IJN.S199104