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PD-1 Blockade During Post-partum Involution Reactivates the Anti-tumor Response and Reduces Lymphatic Vessel Density

Post-partum breast cancer patients, or breast cancer patients diagnosed within 10 years of last childbirth, are ~3–5 times more likely to develop metastasis in comparison to non-post-partum, or nulliparous, patients. Additionally, post-partum patients have increased tumor-associated lymphatic vessel...

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Detalles Bibliográficos
Autores principales: Tamburini, Beth A. Jirón, Elder, Alan M., Finlon, Jeffrey M., Winter, Andrew B., Wessells, Veronica M., Borges, Virginia F., Lyons, Traci R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579890/
https://www.ncbi.nlm.nih.gov/pubmed/31244852
http://dx.doi.org/10.3389/fimmu.2019.01313