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DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells

Nitric Oxide (NO) is an endogenous pulmonary vasodilator produced by endothelial NO synthase (eNOS). Asymmetric dimethyl L‐arginine (ADMA) is an endogenous inhibitor of eNOS activity. In endothelial cells, ADMA is hydrolyzed to L‐citrulline primarily by dimethylarginine dimethyl‐aminohydrolase‐1 (DD...

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Detalles Bibliográficos
Autores principales: Trittmann, Jennifer K., Almazroue, Hanadi, Jin, Yi, Nelin, Leif D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579941/
https://www.ncbi.nlm.nih.gov/pubmed/31209995
http://dx.doi.org/10.14814/phy2.14150