Cargando…

DDAH1 regulates apoptosis and angiogenesis in human fetal pulmonary microvascular endothelial cells

Nitric Oxide (NO) is an endogenous pulmonary vasodilator produced by endothelial NO synthase (eNOS). Asymmetric dimethyl L‐arginine (ADMA) is an endogenous inhibitor of eNOS activity. In endothelial cells, ADMA is hydrolyzed to L‐citrulline primarily by dimethylarginine dimethyl‐aminohydrolase‐1 (DD...

Descripción completa

Detalles Bibliográficos
Autores principales:	Trittmann, Jennifer K., Almazroue, Hanadi, Jin, Yi, Nelin, Leif D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2019
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6579941/ https://www.ncbi.nlm.nih.gov/pubmed/31209995 http://dx.doi.org/10.14814/phy2.14150

Ejemplares similares

PATET ratio by Doppler echocardiography: non-invasive detection of pediatric pulmonary arterial hypertension
por: Trittmann, Jennifer K., et al.
Publicado: (2022)

An arginase‐1 SNP that protects against the development of pulmonary hypertension in bronchopulmonary dysplasia enhances NO‐mediated apoptosis in lymphocytes
por: Trittmann, Jennifer K., et al.
Publicado: (2016)

DDAH1 Deficiency Attenuates Endothelial Cell Cycle Progression and Angiogenesis
por: Zhang, Ping, et al.
Publicado: (2013)

Hypoxic‐induction of arginase II requires EGF‐mediated EGFR activation in human pulmonary microvascular endothelial cells
por: Pool, Caitlyn M., et al.
Publicado: (2018)

Inhibition of DDAH1, but not DDAH2, results in apoptosis of a human trophoblast cell line in response to TRAIL
por: Lumicisi, B.A., et al.
Publicado: (2015)

Assessment of the direct effects of DDAH I on tumour angiogenesis in vivo
por: Papaevangelou, Efthymia, et al.
Publicado: (2018)

Upregulation of DDAH2 Limits Pulmonary Hypertension and Right Ventricular Hypertrophy During Chronic Hypoxia in Ddah1 Knockout Mice
por: Hannemann, Juliane, et al.
Publicado: (2020)

Assessment of DDAH1 and DDAH2 Contributions to Psychiatric Disorders via In Silico Methods
por: Kozlova, Alena A., et al.
Publicado: (2022)

DDAH2 alleviates myocardial fibrosis in diabetic cardiomyopathy through activation of the DDAH/ADMA/NOS/NO pathway in rats
por: Zhu, Zhen-Dong, et al.
Publicado: (2019)

Bronchopulmonary dysplasia and neurodevelopmental outcome in extremely preterm neonates
por: Trittmann, J. K., et al.
Publicado: (2013)

Inhibition of Dimethylarginine Dimethylaminohydrolase (DDAH) Enzymes as an Emerging Therapeutic Strategy to Target Angiogenesis and Vasculogenic Mimicry in Cancer
por: Hulin, Julie-Ann, et al.
Publicado: (2020)

Human lung telocytes could promote the proliferation and angiogenesis of human pulmonary microvascular endothelial cells in vitro
por: Zheng, Yonghua, et al.
Publicado: (2014)

Hypoxic pulmonary endothelial cells release epidermal growth factor leading to vascular smooth muscle cell arginase‐2 expression and proliferation
por: Chen, Bernadette, et al.
Publicado: (2022)

Association of Variability in the DDAH1, DDAH2, AGXT2 and PRMT1 Genes with Circulating ADMA Concentration in Human Whole Blood
por: Hannemann, Juliane, et al.
Publicado: (2022)

Hypermethylation of DDAH2 promoter contributes to the dysfunction of endothelial progenitor cells in coronary artery disease patients
por: Niu, Pan-Pan, et al.
Publicado: (2014)

Evidence for a protective role for the rs805305 single nucleotide polymorphism of dimethylarginine dimethylaminohydrolase 2 (DDAH2) in septic shock through the regulation of DDAH activity
por: Lambden, Simon, et al.
Publicado: (2018)

Association between variation in the genes DDAH1 and DDAH2 and hypertension among Uygur, Kazakh and Han ethnic groups in China: Associação entre variação de genes DDAH1 e DDAH2 com hipertensão nos grupos étnicos uygur, kazakh e han na China
por: Wang, Zhong, et al.
Publicado: (2016)

PECAM EMPs regulate apoptosis in pulmonary microvascular endothelial cells in COPD by activating the Akt signaling pathway
por: Zeng, Yuqin, et al.
Publicado: (2022)

Sequence Variation in DDAH1 and DDAH2 Genes Is Strongly and Additively Associated with Serum ADMA Concentrations in Individuals with Type 2 Diabetes
por: Abhary, Sotoodeh, et al.
Publicado: (2010)

Regulation of DDAH1 as a Potential Therapeutic Target for Treating Cardiovascular Diseases
por: Liu, Xiaoyu, et al.
Publicado: (2013)

Pyrrolidine dithiocarbamate ameliorates endothelial dysfunction in thoracic aorta of diabetic rats by preserving vascular DDAH activity
por: Lu, Chang-Wu, et al.
Publicado: (2017)

Omeprazole does not Potentiate Acute Oxygen Toxicity in Fetal Human Pulmonary Microvascular Endothelial Cells Exposed to Hyperoxia
por: Patel, Ananddeep, et al.
Publicado: (2015)

Comparison of Bevacizumab and Aflibercept for Suppression of Angiogenesis in Human Retinal Microvascular Endothelial Cells
por: Yazdanyar, Amirfarbod, et al.
Publicado: (2023)

Borg5 is required for angiogenesis by regulating persistent directional migration of the cardiac microvascular endothelial cells
por: Liu, Zhonghua, et al.
Publicado: (2014)

Radiation-induced apoptosis in microvascular endothelial cells.
por: Langley, R. E., et al.
Publicado: (1997)

Endothelial Cell Phenotypes are Maintained During Angiogenesis in Cultured Microvascular Networks
por: Motherwell, Jessica M., et al.
Publicado: (2018)

Modulating DDAH/NOS Pathway to Discover Vasoprotective Insulin Sensitizers
por: Lai, Li, et al.
Publicado: (2016)

17β-Estradiol Promotes Angiogenesis of Rat Cardiac Microvascular Endothelial Cells In Vitro
por: Liu, HaiTao, et al.
Publicado: (2018)

Curcumin suppresses intestinal microvascular endothelial cells invasion and angiogenesis induced by activated platelets
por: Xu, Su, et al.
Publicado: (2019)

Fibrin and Collagen Differentially but Synergistically Regulate Sprout Angiogenesis of Human Dermal Microvascular Endothelial Cells in 3-Dimensional Matrix
por: Feng, Xiaodong, et al.
Publicado: (2013)

Role of pulmonary microvascular endothelial cell apoptosis in murine sepsis-induced lung injury in vivo
por: Gill, Sean E., et al.
Publicado: (2015)

Extracellular matrix compression temporally regulates microvascular angiogenesis
por: Ruehle, M. A., et al.
Publicado: (2020)

DDAH1 Promotes Lung Endothelial Barrier Repair by Decreasing Leukocyte Transendothelial Migration and Oxidative Stress in Explosion-Induced Lung Injury
por: Cong, Peifang, et al.
Publicado: (2022)

Endothelial Progenitor Cell-Derived Microvesicles Promote Angiogenesis in Rat Brain Microvascular Endothelial Cells In vitro
por: Zeng, Wen, et al.
Publicado: (2021)

KLF4 Promotes Angiogenesis by Activating VEGF Signaling in Human Retinal Microvascular Endothelial Cells
por: Wang, Yinan, et al.
Publicado: (2015)

Inhibitors of the Hydrolytic Enzyme Dimethylarginine Dimethylaminohydrolase (DDAH): Discovery, Synthesis and Development
por: Murphy, Rhys B., et al.
Publicado: (2016)

DDAH1 Protects against Acetaminophen-Induced Liver Hepatoxicity in Mice
por: Shen, Xiyue, et al.
Publicado: (2022)

DDAH1 Protects against Cardiotoxin-Induced Muscle Injury and Regeneration
por: Feng, Fei, et al.
Publicado: (2023)

Reduning alleviates sepsis-induced acute lung injury by reducing apoptosis of pulmonary microvascular endothelial cells
por: Wang, Ziyi, et al.
Publicado: (2023)

Inhaled nitric oxide for neonates with persistent pulmonary hypertension of the newborn in the CINRGI study: time to treatment response
por: Nelin, Leif D., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_4qb3ev2acmmmm8tkpeggkrh1uh