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Zinc supplementation inhibits the high glucose-induced EMT of peritoneal mesothelial cells by activating the Nrf2 antioxidant pathway

The high glucose (HG)-induced epithelial-mesenchymal transition (EMT) of peritoneal mesothelial cells (PMCs) serves an important role in peritoneal fibrosis (PF) during peritoneal dialysis. Our previous study reported that zinc (Zn) supplementation prevented the HG-induced EMT of rat PMCs in vitro....

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Detalles Bibliográficos
Autores principales: Gao, Lili, Fan, Yi, Zhang, Xiuli, Yang, Lina, Huang, Wenyu, Hang, Tianyu, Li, Mingyang, Du, Shuyan, Ma, Jianfei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580007/
https://www.ncbi.nlm.nih.gov/pubmed/31115566
http://dx.doi.org/10.3892/mmr.2019.10260