Salidroside protects SH-SY5Y from pathogenic α-synuclein by promoting cell autophagy via mediation of mTOR/p70S6K signaling

The abnormal aggregation of α-synuclein (α-syn), which is an important pathological feature of Parkinson's disease (PD), is cytotoxic to dopaminergic neurons and causes cellular damage and apoptosis. Salidroside (SAL) is the main active component of the traditional Chinese medicine Rhodiola ros...

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Detalles Bibliográficos
Autores principales: Chen, Shasha, Cai, Feng, Wang, Jirong, Yang, Zhouxin, Gu, Chi, Wang, Guofu, Mao, Genxiang, Yan, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580031/
https://www.ncbi.nlm.nih.gov/pubmed/31180515
http://dx.doi.org/10.3892/mmr.2019.10285

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580031/
https://www.ncbi.nlm.nih.gov/pubmed/31180515
http://dx.doi.org/10.3892/mmr.2019.10285

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