Fr-HMGB1 and ds-HMGB1 activate the kynurenine pathway via different mechanisms in association with depressive-like behavior

Our previous study reported that fully reduced high mobility group box 1 (fr-HMGB1) and disulfide HMGB1 (ds-HMGB1) induce depressive-like behavior; however, the underlying mechanisms remain unclear. In the present study, the induction of depression via the kynurenine pathway by different redox state...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Lian, Yong-Jie, Su, Wen-Jun, Liu, Lin-Lin, Li, Jia-Mei, Jiang, Chun-Lei, Wang, Yun-Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580048/
https://www.ncbi.nlm.nih.gov/pubmed/31115516
http://dx.doi.org/10.3892/mmr.2019.10225

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580048/
https://www.ncbi.nlm.nih.gov/pubmed/31115516
http://dx.doi.org/10.3892/mmr.2019.10225

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