Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells

Purpose: Inflammation has been strongly associated with retinal damage in diseases such as diabetic retinopathy. Several studies have reported that high glucose exposure induces damage to the retinal vasculature. We and others have shown that high glucose can activate the NOD-like receptor family, p...

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Detalles Bibliográficos
Autores principales: Jiang, Youde, Steinle, Jena J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2019
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580119/
https://www.ncbi.nlm.nih.gov/pubmed/31354329
http://dx.doi.org/10.2147/JIR.S210441

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580119/
https://www.ncbi.nlm.nih.gov/pubmed/31354329
http://dx.doi.org/10.2147/JIR.S210441

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