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Epac1 inhibits PKR to reduce NLRP3 inflammasome proteins in retinal endothelial cells
Purpose: Inflammation has been strongly associated with retinal damage in diseases such as diabetic retinopathy. Several studies have reported that high glucose exposure induces damage to the retinal vasculature. We and others have shown that high glucose can activate the NOD-like receptor family, p...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Dove
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580119/ https://www.ncbi.nlm.nih.gov/pubmed/31354329 http://dx.doi.org/10.2147/JIR.S210441 |