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In the absence of UCP1-mediated diet-induced thermogenesis, obesity is augmented even in the obesity-resistant 129S mouse strain
The attractive tenet that recruitment and activation of brown adipose tissue (BAT) and uncoupling protein 1 (UCP1) could counteract the development of obesity and its comorbidities in humans has been experimentally corroborated mainly by experiments demonstrating that UCP1-ablated mice on a C57Bl/6...
Autores principales: | Luijten, Ineke H. N., Feldmann, Helena M., von Essen, Gabriella, Cannon, Barbara, Nedergaard, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Physiological Society
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580168/ https://www.ncbi.nlm.nih.gov/pubmed/30807213 http://dx.doi.org/10.1152/ajpendo.00020.2019 |
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