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Hepatotoxicity Due to Azole Antimycotic Agents in a HLA B*35:02-Positive Patient

We will present a 42-year-old woman with acute myeloid leukemia and pulmonary aspergillosis. She was treated with several antifungal agents, including three triazoles. Voriconazole, posaconazole, and isavuconazole all led to hepatocellular liver injury. Voriconazole administration led to a peak alan...

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Detalles Bibliográficos
Autores principales: Bühler, Tim, Medinger, Michael, Bouitbir, Jamal, Krähenbühl, Stephan, Leuppi-Taegtmeyer, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580185/
https://www.ncbi.nlm.nih.gov/pubmed/31244659
http://dx.doi.org/10.3389/fphar.2019.00645