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Structural and functional characterization of CMP-N-acetylneuraminate synthetase from Vibrio cholerae

Several pathogenic bacteria utilize sialic acid, including host-derived N-acetylneuraminic acid (Neu5Ac), in at least two ways: they use it as a nutrient source and as a host-evasion strategy by coating themselves with Neu5Ac. Given the significant role of sialic acid in pathogenesis and host-gut co...

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Detalles Bibliográficos
Autores principales: Bose, Sucharita, Purkait, Debayan, Joseph, Deepthi, Nayak, Vinod, Subramanian, Ramaswamy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580227/
https://www.ncbi.nlm.nih.gov/pubmed/31205019
http://dx.doi.org/10.1107/S2059798319006831