Melibiosamine, a novel oligosaccharide, suppresses mitogen-induced IL-2 production via inactivation of NFAT and NFκB in Jurkat cells

d-Glucosamine (GlcNH(2)) and several of its derivatives are known to possess immunosuppressive activities in various immune cell lines. The novel GlcNH(2)-containing oligosaccharide Galα1-6GlcNH(2) (designated melibiosamine; MelNH(2)) is expected to be immunosuppressive also. In Jurkat cells (immort...

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Detalles Bibliográficos
Autores principales: Fujita, Kazuki, Tanaka, Susumu, Iizumi, Kyoichi, Akiyama, Shuri, Uchida, Kaoru, Ogata, Makoto, Aoki, Daichi, Hosomi, Osamu, Kubohara, Yuzuru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580327/
https://www.ncbi.nlm.nih.gov/pubmed/31431927
http://dx.doi.org/10.1016/j.bbrep.2019.100658

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580327/
https://www.ncbi.nlm.nih.gov/pubmed/31431927
http://dx.doi.org/10.1016/j.bbrep.2019.100658

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