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Melibiosamine, a novel oligosaccharide, suppresses mitogen-induced IL-2 production via inactivation of NFAT and NFκB in Jurkat cells
d-Glucosamine (GlcNH(2)) and several of its derivatives are known to possess immunosuppressive activities in various immune cell lines. The novel GlcNH(2)-containing oligosaccharide Galα1-6GlcNH(2) (designated melibiosamine; MelNH(2)) is expected to be immunosuppressive also. In Jurkat cells (immort...
Autores principales: | Fujita, Kazuki, Tanaka, Susumu, Iizumi, Kyoichi, Akiyama, Shuri, Uchida, Kaoru, Ogata, Makoto, Aoki, Daichi, Hosomi, Osamu, Kubohara, Yuzuru |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580327/ https://www.ncbi.nlm.nih.gov/pubmed/31431927 http://dx.doi.org/10.1016/j.bbrep.2019.100658 |
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