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Direct Inhibition of MmpL3 by Novel Antitubercular Compounds

[Image: see text] MmpL3, an essential transporter involved in the export of mycolic acids, is the proposed target of a number of antimycobacterial inhibitors under development. Whether MmpL3 serves as the direct target of these compounds, however, has been called into question after the discovery th...

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Detalles Bibliográficos
Autores principales: Li, Wei, Stevens, Casey M., Pandya, Amitkumar N., Darzynkiewicz, Zbigniew, Bhattarai, Pankaj, Tong, Weiwei, Gonzalez-Juarrero, Mercedes, North, E. Jeffrey, Zgurskaya, Helen I., Jackson, Mary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2019
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580365/
https://www.ncbi.nlm.nih.gov/pubmed/30882198
http://dx.doi.org/10.1021/acsinfecdis.9b00048