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Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression
BACKGROUND: The wide variety of specialized permissive and repressive mechanisms by which germ cells regulate developmental gene expression are not well understood genome-wide. Isolation of germ cells with high integrity and purity from living animals is necessary to address these open questions, bu...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580472/ https://www.ncbi.nlm.nih.gov/pubmed/31208332 http://dx.doi.org/10.1186/s12864-019-5893-9 |