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Isolated C. elegans germ nuclei exhibit distinct genomic profiles of histone modification and gene expression

BACKGROUND: The wide variety of specialized permissive and repressive mechanisms by which germ cells regulate developmental gene expression are not well understood genome-wide. Isolation of germ cells with high integrity and purity from living animals is necessary to address these open questions, bu...

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Detalles Bibliográficos
Autores principales: Han, Mei, Wei, Guifeng, McManus, Catherine E., Hillier, LaDeana W., Reinke, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580472/
https://www.ncbi.nlm.nih.gov/pubmed/31208332
http://dx.doi.org/10.1186/s12864-019-5893-9