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New α- and SIN γ-retrovectors for safe transduction and specific transgene expression in pancreatic β cell lines

BACKGROUND: Viral vectors are invaluable tools to transfer genes and/or regulatory sequences into differentiated cells such as pancreatic cells. To date, several kinds of viral vectors have been used to transduce different pancreatic cell types, including insulin-producing β cells. However, few stud...

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Detalles Bibliográficos
Autores principales: Albagli, Olivier, Maugein, Alicia, Huijbregts, Lukas, Bredel, Delphine, Carlier, Géraldine, Martin, Patrick, Scharfmann, Raphaël
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580483/
https://www.ncbi.nlm.nih.gov/pubmed/31208395
http://dx.doi.org/10.1186/s12896-019-0531-9