Computational analysis of receptor tyrosine kinase inhibitors and cancer metabolism: implications for treatment and discovery of potential therapeutic signatures

BACKGROUND: Receptor tyrosine kinase (RTK) inhibitors are frequently used to treat cancers and the results have been mixed, some of these small molecule drugs are highly successful while others show a more modest response. A high number of studies have been conducted to investigate the signaling mec...

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Detalles Bibliográficos
Autores principales: Li, Jian, Halfter, Kathrin, Zhang, Mengying, Saad, Christian, Xu, Kai, Bauer, Bernhard, Huang, Yijiang, Shi, Lei, Mansmann, Ulrich R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580552/
https://www.ncbi.nlm.nih.gov/pubmed/31208363
http://dx.doi.org/10.1186/s12885-019-5804-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580552/
https://www.ncbi.nlm.nih.gov/pubmed/31208363
http://dx.doi.org/10.1186/s12885-019-5804-0

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