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SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model
BACKGROUND: Right ventricular (RV) angiogenesis has been associated with adaptive myocardial remodeling in pulmonary hypertension (PH), though molecular regulators are poorly defined. Endothelial cell VEGFR-2 is considered a “master regulator” of angiogenesis in other models, and the small molecule...
Autores principales: | Peloquin, Grace L., Johnston, Laura, Damarla, Mahendra, Damico, Rachel L., Hassoun, Paul M., Kolb, Todd M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580559/ https://www.ncbi.nlm.nih.gov/pubmed/31208454 http://dx.doi.org/10.1186/s12931-019-1079-x |
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