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A systematic analysis of genomics-based modeling approaches for prediction of drug response to cytotoxic chemotherapies

BACKGROUND: The availability and generation of large amounts of genomic data has led to the development of a new paradigm in cancer treatment emphasizing a precision approach at the molecular and genomic level. Statistical modeling techniques aimed at leveraging broad scale in vitro, in vivo, and cl...

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Detalles Bibliográficos
Autores principales: Mannheimer, Joshua D., Duval, Dawn L., Prasad, Ashok, Gustafson, Daniel L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580596/
https://www.ncbi.nlm.nih.gov/pubmed/31208429
http://dx.doi.org/10.1186/s12920-019-0519-2