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Distribution differences in prognostic copy number alteration profiles in IDH-wild-type glioblastoma cause survival discrepancies across cohorts

The diagnosis and prognostication of glioblastoma (GBM) remain to be solely dependent on histopathological findings and few molecular markers, despite the clinical heterogeneity in this entity. To address this issue, we investigated the prognostic impact of copy number alterations (CNAs) using two p...

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Detalles Bibliográficos
Autores principales: Umehara, Toru, Arita, Hideyuki, Yoshioka, Ema, Shofuda, Tomoko, Kanematsu, Daisuke, Kinoshita, Manabu, Kodama, Yoshinori, Mano, Masayuki, Kagawa, Naoki, Fujimoto, Yasunori, Okita, Yoshiko, Nonaka, Masahiro, Nakajo, Kosuke, Uda, Takehiro, Tsuyuguchi, Naohiro, Fukai, Junya, Fujita, Koji, Sakamoto, Daisuke, Mori, Kanji, Kishima, Haruhiko, Kanemura, Yonehiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580599/
https://www.ncbi.nlm.nih.gov/pubmed/31215469
http://dx.doi.org/10.1186/s40478-019-0749-8