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HIV-1 subtype C Envelope function becomes less sensitive to N-glycosylation deletion during disease progression

OBJECTIVE: As part of a larger study to understand how Envelope N-glycosylation influences HIV-1 pathogenesis, we selected a participant infected with a single Subtype C variant and determined whether deletion of specific potential N-glycan sites (PNGs) impacted Envelope function longitudinally. RES...

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Detalles Bibliográficos
Autores principales: Lumngwena, Evelyn Ngwa, Shuping, Liliwe, Bernitz, Netanya, Woodman, Zenda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6580609/
https://www.ncbi.nlm.nih.gov/pubmed/31208438
http://dx.doi.org/10.1186/s13104-019-4375-0